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Career opportunities

Editor-in-Chief of The Journal of Physiology

Closing date: 12 July 2021
Apply: www.physoc.org/job_vacancy/editor-in-chief-of-the-journal-of-physiology

The Physiological Society is seeking a visionary Editor-in-Chief for The Journal of Physiology, one of the world’s most distinguished scientific publications. The editorship is a highly influential position in physiology and gives the Editor-in-Chief a unique opportunity to shape The Journal and the direction of physiological research.

Applications are sought from visionary researchers who can help shape the future of one of the world’s most highly influential and distinguished physiology journals.

Postdoctoral position in Developmental Programming, Department of Pediatrics, University of Michigan, USA

Apply: Send application details (see below) to Dr. Vasantha Padmanabhan at vasantha@umich.edu
Informal enquiries: Email Dr. Vasantha Padmanabhan at vasantha@umich.edu

About the role

A postdoctoral position is available in the laboratory of Dr. Vasantha Padmanabhan in the Department of Pediatrics, University of Michigan. For this position, we are seeking a highly motivated postdoctoral researcher to investigate the molecular mechanisms underlying the impact of prenatal exposure to native steroids / environmental disrupting chemicals in programming reproductive and cardiometabolic dysfunction. The ideal candidate will have a Ph.D. degree in biological / health sciences (or related field) and a strong background in molecular biology techniques.

Specific Position Duties

Research (100%)

  • Perform experiments using advanced biomedical research techniques
  • Have the primary responsibility for writing scientific publications
  • Present the results at national and international scientific meetings
  • Participate in writing grant applications
  • Participate in large animal investigation

Qualifications

Minimum Requirements:

  • PhD in relevant scientific area including Molecular Biology and Cell Biology, Reproductive Biology and/or Biochemistry
  • Knowledge and hands on experience in molecular biology techniques (see desired skills below)
  • Excellent communication and organizational skills
  • Ability to work independently but also a team player
  • A strong work ethic and a commitment to becoming an independent scientist
  • Demonstrated skills in scientific writing (based on publication record)

Desired or preferred previous experience with:

  • molecular assays (DNA/RNA isolation
  • quantitative RT-PCR), blotting/probing
  • histology
  • immunohistochemistry
  • microscopy
  •  imaging and data analyses
  • RNA seq.

Application materials

  • Cover letter 1-page description of research experience as well as qualifications and interest in this position
  • CV including prior positions, publications and technical expertise
  • Contact information of three references who may be contacted

 

Postdoctoral Fellowship, National Institutes of Health (NIH) and National Institute of Neurological Disorders and Stroke (NINDS), Washington, USA

Closing date: The position is available now and will remain open until filled.
Department: Cellular and Developmental Neurobiology Section (CNDS), Division of Intramural Research (DIR), Department of Health and Human Service
Apply: Email Dr. Susan Wray (wrays@ninds.nih.gov) with an updated C.V.
Website: CDNS https://dir.ninds.nih.gov/Faculty/Profile/susan-wray.html and DIR https://dir.ninds.nih.gov/

About the role

The successful candidate must have an Ph.D., M.D. or D.O. degree or equivalent, and relevant training in Neurobiology, Neuroendocrinology, Molecular biology, or Developmental biology. The candidate must be less than 2 years out from obtaining their Ph.D. Descriptions of the projects performed in research areas are indicated below. and cover letter. The NIH is dedicated to building a diverse community in its training and employment programs.

Neurodevelopment description

Work encompasses Cell lineage, Neuronal Migration, Axonal Targeting, Craniofacial development and Understanding mutations identified in patients with Kallmann Syndrome. Projects focus on migration of GnRH cells, development of olfactory ensheathing cells and olfactory axon outgrowth during development of the craniofacial region.

Current projects examine:

  1. lineage of the GnRH cells
  2. axon targeting
  3. biology of genes identified in patients with delayed puberty and anosmia, and
  4. development of the craniofacial region. Candidates with experience in mouse development, molecular and imaging techniques preferred but not mandatory.

Recent work:

  • Saglam A, Calof AC, Wray S. A Novel Factor in Olfactory Ensheathing Cell-Astrocyte Crosstalk: Anti-Inflammatory Protein α-Crystallin B. Glia, 2020.
  • Shan, Y. Farmer, SM, Wray, S. Drebrin Regulates Cytoskeleton Dynamics in Migrating Neurons through Interaction with CXCR4. PNAS, 2021.

Mechanisms underlying Neuronal Activity Description

Projects focus on the mechanisms underlying neuronal activity using GnRH neurons as the model system. In vivo, GnRH neurons, spread throughout the forebrain, release GnRH in a pulsatile fashion to control reproduction. In explants, primary GnRH neurons continue to release in a pulsatile fashion and show synchronized calcium oscillations. Projects utilize the GnRH system to study molecular and cellular properties of neuronal activity (individual cells and neuronal population dynamics) and correlate activity with secretion. Candidates with experience in calcium imaging or electrophysiology, molecular biology and mouse anatomy preferred but not mandatory.

Recent work:

  • Constantin S, Wray S. Nociceptin/Orphanin-FQ inhibits gonadotropin releasing hormone neurons via G-protein gated inwardly rectifying potassium channels. eNeuro. 2018 Dec 26;5(6).
  • Constantin S, Reynolds, D. Oh, A, Pizano K, Wray S. Nitric oxide resets kisspeptin-excited GnRH neurons via PIP2 replenishment. PNAS, 2021.

The laboratory in which the candidate will work utilizes multidisciplinary approaches such as, cre/lox mice, immunocytochemistry, video microscopy, calcium imaging, electrophysiology, in situ histochemistry, single-cell PCR, and subtractive cDNA screening. Salary will be commensurate with experience.