Senior Postdoctoral Scientist, Imperial Colleage London, UK
Seyed M. Ghiasi (ORCID: 0000-0001-8526-8513) received his PhD in cellular and genetic medicine focusing on understanding molecular mechanisms of inflammatory and metabolic stresses including 1) RNA metabolism in inflammatory and metabolic stresses, 2) inflammasome complex contribution to dysfunction and death of pancreatic beta cells, 3) pharmacological intervention of gap-junction modifying targets in pancreatic beta cells, 4) the role of chaperons in insulin folding. Next, he accomplished his first postdoc research on live cell imaging of extracellular ATP in pancreatic beta cells and then received several prestigious grants to pursue his senior postdoc research in the professor Guy Rutter Lab, Section of Cell Biology, Division of Diabetes, Endocrinology and Metabolism, Imperial College London. His ongoing project is aimed to study on the impact of deficiency of the RNA decay pathways (i.e. No-Go Decay (NGD) and Nonsense-Mediated Decay (NMD) on pancreatic beta cell function and survival using human/rodent islets and cell lines, and transgenic mice.